Publications

See a complete PubMed list of publications by David M. Engman, MD, PhD.


Selected Key Publications

Brown RW, Sharma AI, Engman DM. Dynamic protein S-palmitoylation mediates parasite life cycle progression and diverse mechanisms of virulence. Crit Rev Biochem Mol Biol. 2017 Apr;52(2):145-162. http://www.tandfonline.com/doi/full/10.1080/10409238.2017.1287161.

Pasternack DA, Sharma AI, Olson CL, Epting CL, Engman DM. Sphingosine kinase regulates microtubule dynamics and organelle positioning necessary for proper G1/S cell cycle transition in Trypanosoma brucei. mBio. 2015;6(5):e01291-15. http://mbio.asm.org/content/6/5/e01291-15.

Bonney KM, Engman DM. Autoimmune pathogenesis of Chagas heart disease: looking back, looking ahead. Am J Pathol. 2015 Jun;185(6):1537-1547. http://ajp.amjpathol.org/article/S0002-9440(15)00151-0/abstract.

Maric D, McGwire BS, Buchanan KT, Olson CL, Emmer BT, Epting CL, Engman DM. Molecular determinants of ciliary membrane localization of Trypanosoma cruzi flagellar calcium-binding protein. J Biol Chem. 2011 Sep 23;286:33109-33117. http://www.jbc.org/content/286/38/33109.full.

Bonney KM, Taylor JM, Daniels MD, Epting CL, Engman DM. Heat-killed Trypanosoma cruzi induces acute cardiac damage and polyantigenic autoimmunity. PLOS One. 2011;6(1):e14571. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0014571.

Emmer BT, Nakayasu ES, Souther C, Choi H, Sobreira TJ, Epting CL, Nesvizhii AI, Almeida IC, Engman DM. Global analysis of protein palmitoylation in African trypanosomes. Eukaryot Cell. 2011;10(3):455-463. http://ec.asm.org/content/10/3/455.

Emmer BT, Maric D, Engman DM. Molecular mechanisms of protein and lipid targeting to ciliary membranes. J Cell Sci. 2010;123(Pt 4):529-536. http://jcs.biologists.org/content/123/4/529.

Emmer BT, Souther C, Toriello KM, Olson CL, Epting CL, Engman DM. Identification of a palmitoyl acyltransferase required for protein sorting to the flagellar membrane. J Cell Sci. 2009;122(Pt 6):867-874. http://jcs.biologists.org/content/122/6/867.

Tyler KM, Fridberg A, Toriello KM, Olson CL, Cieslak JA, Hazlett TL, Engman DM. Flagellar membrane localization via association with lipid rafts. J Cell Sci. 2009;122(Pt 6):859-866. http://jcs.biologists.org/content/122/6/859.

Hyland KV, Asfaw SH, Olson CL, Daniels MD, Engman DM. Bioluminescent imaging of Trypanosoma cruzi infection. Int J Parasitol. 2008 Oct;38(12):1391-1400. http://www.sciencedirect.com/science/article/pii/S0020751908001458.

Fridberg A, Olson CL, Nakayasu ES, Tyler KM, Almeida IC, Engman DM. Sphingolipid synthesis is necessary for kinetoplast segregation and cytokinesis in Trypanosoma brucei. J Cell Sci. 2008;121(Pt 4):522-535. http://jcs.biologists.org/content/121/4/522.long.

Hyland KV, Leon JS, Daniels MD, Giafis N, Woods LM, Bahk TJ, Wang K, Engman DM. Modulation of autoimmunity by treatment of an infectious disease. Infect Immun. 2007 Jul;75(7):3641-3650. http://iai.asm.org/content/75/7/3641.

Tyler KM, Luxton GWG, Applewhite DA, Murphy SC, Engman DM. Responsive microtubule dynamics promote cell invasion by Trypanosoma cruzi. Cell Microbiol. 2005 Nov;7(11):1579-1591. http://onlinelibrary.wiley.com/doi/10.1111/j.1462-5822.2005.00576.x/abstract.